Clem Jones Centre for Ageing Dementia Research Public Dementia Forum
- Full Description:
- QBI Director Professor Pankaj Sah and the Director of the Clem Jones Centre for Ageing Dementia Research (CJCADR), Professor Jürgen Götz, invite you to a half day public dementia forum on Thursday 11th May. The forum will cover living well with dementia and updates on CJCADR research discoveries.
Opening the forum
Professor Aiden Byrne, Provost, Senior Vice-President University of Queensland
Living well with dementia
Mr John Quinn, Dementia advocate
Care perspective, engaging with people living with dementia
Ms Tara Quirke, Consumer Directed Research Network
Brisbane Diamantina Health Partners Ageing Theme
Professor Leonard Gray, Director Centre for Research in Geriatric Medicine, UQ, Director Centre for Inline Health, UQ Consultant Geriatrician, PAH
The immune system in Alzheimers disease
Dr Rodrigo Medeiros, Group Leader Clem Jones Centre for Ageing Dementia Research
World first clinical trial to develop public health guidelines as to how exercise can both prevent and reverse dementia
Professor Perry Bartlett, Foundation Professor Molecular Neuroscience, Queensland Brain Institute, Clem Jones Centre for Ageing Dementia Research
Ultrasound the story so far
Mr Matthew Pelekanos, Ultrasound Research Manager, Clem Jones Centre for Ageing Dementia Research
Ultrasound mediated delivery of engineered antibodies as a therapy
Dr Rebecca Nisbet, Clem Jones Centre for Ageing Dementia Research
This is a free event but registration is essential for catering. Please register here.
About Public Dementia Forum Series
This yearly public forum looks at living with dementia, its treatment, and Clem Jones Centre for Ageing Dementia Research discoveries.
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Dementia research at the University of Queensland ranges from understanding the basis of the disease, through to treatments and developing better care options.
Led by Professor Jürgen Götz, scientists at QBI’s Clem Jones Centre for Ageing Dementia Research (CJCADR) are developing a non-invasive ultrasound technology to treat Alzheimer’s disease and restore memory. The approach temporarily opens the blood-brain barrier, activating mechanisms that clear toxic protein clumps, and restoring memory functions. Research has been conducted in mouse models and is being scaled up in higher animal models. This breakthrough research is bringing hope to the hundreds of thousands of Australians currently living with the illness.
The research undertaken by CJCADR investigates, at a biochemical, molecular, behavioural, electrophysiological and histological and systems level, how ageing dementia causes neurodegeneration as well as the decline of memory and also, motor functions. This is complemented by studies into physiological ageing. The Centre uses as experimental systems mainly tissue culture cells and genetically modified mice and worms.
Exercise may be an effective way of decreasing the risk of cognitive decline. QBI Founding Director Professor Perry Bartlett successfully used exercise to improve cognition in older mice. He is now leading the clinical trial, along with Dr Mia Schaumberg, from the UQ School of Human Movement and Nutrition Sciences, to find the amount, intensity, and type of exercise that might lead to cognitive improvement in elderly people. It’s thought that exercise boosts the production of new neurons in the brain, which might improve cognition. Ultimately, the aim is to have clear public health guidelines as to how exercise can both prevent and reverse dementia. qbi.uq.edu.au/exercise-study
Researchers such as Professor David Fairlie at the Institute for Molecular Bioscience's Centre for Inflammation and Disease Research are investigating how to stop inflammation and the diseases it can cause, including dementia. Dr Rodrigo Medeiros at QBI’s Clem Jones Centre for Ageing Dementia Research is also trying to find biomarkers that signpost the initial inflammatory response in Alzheimer's disease. From this he hopes to identify promising compounds that could help stop chronic inflammation.
CJCADR is pursuing new strategies to reduce the burden of dementia. This includes the development of therapeutic antibodies. A major aim is the discovery of interventions to delay the onset, prevent and even cure dementia in patients, using novel drugs and better methods to deliver them to the brain. Another aim is the development of biomarkers to diagnose dementia earlier, more cheaply and with greater accuracy, and to monitor therapeutic interventions. Finally, lifestyle strategies will be formulated for maintaining a healthy brain.
People who suffer from sleep apnoea are two to three times more likely to develop Alzheimer’s disease, says Professor Elizabeth Coulson, from the Queensland Brain Institute and the School of Biomedical Sciences at UQ.
“This could be because hypoxia – lower levels of oxygen in the blood from poor breathing – causes nerve cell death,” she says.
Prof Coulson’s team is beginning a study that will follow patients aged 55 to 75 with sleep apnoea over an extended period, to determine whether using a continuous positive airway pressure (CPAP) ventilator, which keeps airways open during sleep, protects against brain degeneration and lowers the risk of dementia.qbi.uq.edu.au/sleepapnoeastudy
Enhancing Language Learning in Ageing with Exercise
This UQ study aims to understand how exercising affects learning, by training older people to learn new words immediately before or after they exercise. Understanding how exercise affects language learning may lead to new approaches for improving language re-learning in older people with brain conditions. exercise-ella.com
Ageing Mind Initiative
The Ageing Mind Initiative (AMI) is a UQ virtual clinical ageing research group coordinated by Professor Nancy Pachana from the School of Psychology, and Professor Gerard Byrne from Psychiatry in the Faculty of Medicine. AMI provides a focal point for clinical, translational ageing research in a mental health context. ami.group.uq.edu.au
CarFreeMe is an evidence-based method to help older people transition from driving. The program is for people with dementia or brain injury and stroke survivors. CarFreeMe works on the basic principles of empowerment, support and understanding. carfreeme.com.au
Early detection of dementia
UQ’s Centre for Health Services is developing an electronic system to improve early detection of dementia when people go to see their GPs. The research also aims to find ways to support GPs in helping patients to reduce their risk factors and change behaviours.